Review of Medical Practice
type: channel
description: Review of Medical Practice ISSN 2956-4441 ISSN on-line 2956-445X The journal has been published at the University since 2022 as a continuation of the quarterly „International Review of Medical Practice”, issued since 1995. Its formal acquisition, the change of title to „Review of Medical Practice”, and the assignment of new ISSN numbers have enabled further development while maintaining its scholarly mission, tradition, publication record, and continuity of volume numbering. The spectrum of interest of the journal includes original and clinical papers in the field of all medical sciences. The journal is available in databases, repositories, and online search tools: Index Copernicus EBSCO (Academic Search Ultimate; Central & Eastern European Academic Source - CEEAS) Google Scholar OPEN (CeON) Biblioteka Nauki Cyfrowa Biblioteka Narodowa Polona
publisher: Oficyna Wydawnicza Uczelni Łazarskiego
language: en
publication name: Review of Medical Practice
issn: 2956-4441
items: Depresja u osób w wieku senioralnym jako problem zdrowia publicznego w Polsce. Przegląd literatury
items: Ciężki przypadek malarii powikłanej niedokrwistością autoimmunohemolityczną w przebiegu leczenia dożylnym artesunatem
items: Ocena funkcjonowania osób z niepełnosprawnościami - aktualne perspektywy i wyzwania
items: Selected Problems Related to a Stroke – a Physiotherapist’s Perspective
items: World mental health report. Transforming mental health for all.
items: Polikarp Girsztowt (1827–1877) and His Few Words about Leprosy
items: The Absence of Leprosy in the Polish Population from the 16th to the 21st Century
items: Leprosy in XXIst Europe
items: Rickettsial Infections and Q Fever as Underestimated Health Threats to Humans
items: The Role of Ticks in the Epidemiology of Selected Transmissible Infectious Diseases
items: Neglected Tick-Borne Diseases with a High Epidemiological Risk of Expansiveness
items: Actinomycosis as an Unexpected Cause of Chronic General- ized Lymphadenopathy
items: Effect of Caesarean Section on Subsequent Child Development
items: Shingles and Its Preventative Possibilities in Poland
items: Paradoxical Skin Reaction in Patients with Rheumatoid Arthritis Treated with TNF-α Inhibitors
items: Dapsone – Should It Be Considered as a Treatment Option for Acne, Rosacea and Hidradenitis Suppurativa?

Depresja u osób w wieku senioralnym jako problem zdrowia publicznego w Polsce. Przegląd literatury
type: item
description: The aim of the study is to determine the prevalence of depression in seniors on the basis of available literature. The article addresses the issue of depression in the senior population, analyzes factors influencing the occurrence of depressive symptoms, discusses the topic of suicide attempt within this age group, and presents coping strategies for dealing with this illness. Depression among older adults is a significant public health concern, and educating society is crucial due to the ongoing increase in the number of elderly individuals in the population and the rising incidence of depression, in order to effectively improve the quality of life for seniors.
subject: Artykuły
  topic: section
subject: depression
  topic: keywords
subject: seniors
  topic: keywords
subject: factors
  topic: keywords
subject: prevention
  topic: keywords
subject: medycyna
  topic: disciplines
subject: nauki o zdrowiu
  topic: disciplines
subject: psychiatria
  topic: disciplines
subject: psychologia
  topic: disciplines
creator: Natalia Kucharska
creator: Magdalena Rękas
creator: Joanna Burzyńska
creator: Małgorzata Nagórska
rights: Copyright (c) 2026 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-01-04
publication date: 2026-01-04

Ciężki przypadek malarii powikłanej niedokrwistością autoimmunohemolityczną w przebiegu leczenia dożylnym artesunatem
type: item
description: Malaria is a severe parasitic disease caused by a protozoan of the Plasmodium genus, widespread in the worm climate tropical areas. High temperatures and humidity favor the multiplication of the malaria vector – the Anopheles mosquito, whose female is responsible for the transmission of the infection in the natural environment. The study presents a complicated case of malaria caused by P. falciparum with a high parasitemia of 11% and symptoms of multi-organ injuries – acute renal failure with black water fever and anuria, impaired consciousness related to ischaemia of the brain with cerebral malaria, hemorrhagic diathesis, respiratory distress, liver damage, hyperpyrexia, hypotension, which developed as a result of delayed diagnosis and transport of the patient to a tropical centre. The patient stayed in Guinea for 2 weeks for business purposes, without using pharmacological prophylaxis against malaria recommended for this geographical zone of the world. A similarly severe clinical picture of malaria was observed in a colleague from Belgium, who was treated at the same time in his country. The therapy included intravenous artesunate and symptomatic treatment, achieving complete eradication of parasitaemia from peripheral blood already on the 3rd day of antimalarial pharmacotherapy. In the 3rd week of hospitalization during the convalescence period, there were signs of rapidly deepening anaemia not related to recurrence of infection, ineffective therapy, or resistance to the antimalarial drugs used. Immunodiagnostic tests detecting the presence of immunoglobulin IgG coating the patient’s erythrocytes confirmed acute haemolytic anaemia of autoimmune aetiology following artesunate therapy. In the treatment of the rare complication, blood transfusions and systemic steroids were used with a positive therapeutic effect. Treatment of complicated cases of malaria requiring parenteral artemisinin preparations should be carried out in reference centres with documented practic…
subject: Artykuły
  topic: section
subject: complicated malaria
  topic: keywords
subject: Plasmodium falciparum
  topic: keywords
subject: sequelae
  topic: keywords
subject: artesunate
  topic: keywords
subject: autoimmune haemolytic anaemia
  topic: keywords
subject: medycyna
  topic: disciplines
subject: nauki o zdrowiu
  topic: disciplines
creator: Kamil Kosal
creator: Julia Zosik
creator: Karolina Kawińska
creator: Iwona Anderko
creator: Joanna Swarcewicz
creator: Małgorzata Paul
rights: Copyright (c) 2026 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-01-04
publication date: 2026-01-04

Ocena funkcjonowania osób z niepełnosprawnościami - aktualne perspektywy i wyzwania
type: item
description: The contemporary approach to functional assessment of persons with disabilities abandons the traditional medical model in favour of a holistic perspective based on the International Classification of Functioning, Disability and Health (ICF). The article analyses the evolution of disability models, moving from a medical approach, through social approaches, to the current bio-psychosocial model, which is reflected in the ICF. This classification replaced the earlier ICI DH (International Classification of Impairments, Disabilities, and Handicaps), which focused on health impairments. The new ICF approach assumes that disability is the result of interactions between a person’s health condition and environmental and personal factors. This classification does not evaluate people, but only describes their functioning in various spheres of life. The article discusses ICF-related, diagnosis-independent assessment tools such as WHODAS 2.0. It also presents the use of functional assessment in various contexts and discusses the role of modern technologies such as wearable sensors and artificial intelligence.
subject: Artykuły
  topic: section
subject: functional assessment
  topic: keywords
subject: ICF
  topic: keywords
subject: WHODAS
  topic: keywords
subject: disability
  topic: keywords
subject: rehabilitation
  topic: keywords
subject: support system
  topic: keywords
subject: inclusion
  topic: keywords
subject: technology
  topic: keywords
subject: medycyna
  topic: disciplines
subject: nauki o zdrowiu
  topic: disciplines
creator: Krzysztof Mirosław Czechowski
rights: Copyright (c) 2026 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-01-04
publication date: 2026-01-04

Selected Problems Related to a Stroke – a Physiotherapist’s Perspective
type: item
description: Stroke affects approximately 80,000 people in Poland annually. It is the third leading cause of death (second worldwide) and the leading cause of adult disability globally. Stroke poses a challenge for medical teams, especially physiotherapists, and a socioeconomic problem. Loss of locomotion and falls are significant after stroke (affecting 7% of people in the first week after stroke, gradually increasing to 55–73% after a year). The causes of falls after stroke are usually complex (balance disorders, locomotion deficits, cognitive impairment, depression, PTSD). Falls carry the risk of fractures, hospitalization, subsequent strokes, impaired concentration, motivation, sense of security, and fear of activity, limiting the patient’s participation in rehabilitation, daily life, and social life. The article provides epidemiological data on these issues, the overall costs incurred by states and societies for treatment, rehabilitation, and stroke-related services, and discusses the mental health of stroke survivors and their loved ones. It highlights the fact that physiotherapists can significantly improve not only the physical but also the mental health and well-being of stroke survivors. They spend relatively more time with patients than other healthcare professionals, often establish closer relationships with them, can be the first to highlight disturbing depressive symptoms that families sometimes overlook, can contact a psychologist, and above all, can strengthen motivation, for example, by conveying hope that physiotherapy will enable them to return to functioning and daily life.
subject: Artykuły
  topic: section
subject: stroke
  topic: keywords
subject: physiotherapy
  topic: keywords
subject: falls
  topic: keywords
subject: medycyna
  topic: disciplines
subject: nauki o zdrowiu
  topic: disciplines
subject: psychologia
  topic: disciplines
creator: Adam Gostyński
creator: Paulina Rosińska
creator: Zofia Konopielko
creator: Jerzy T. Marcinkowski
rights: Copyright (c) 2026 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-01-04
publication date: 2026-01-04

World mental health report. Transforming mental health for all.
type: item
description: Mental health is critically important to everyone, everywhere. All over the world, mental health needs are high but responses are insufficient and inadequate. The World mental health report: transforming mental health for all is designed to inspire and inform better mental health for everyone everywhere. Drawing on the latest evidence available, showcasing examples of good practice from around the world, and voicing people’s lived experience, it highlights why and where change is most needed and how it can best be achieved. It calls on all stakeholders to work together to deepen the value and commitment given to mental health, reshape the environments that influence mental health, and strengthen the systems that care for mental health.
subject: Artykuły
  topic: section
subject: zdrowie psychiczne
  topic: keywords
subject: WHO
  topic: keywords
subject: raport
  topic: keywords
rights: Copyright (c) 2026 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-01-04
publication date: 2026-01-04

World mental health report. Transforming mental health for all.
type: item
description: Mental health is critically important to everyone, everywhere. All over the world, mental health needs are high but responses are insufficient and inadequate. The World mental health report: transforming mental health for all is designed to inspire and inform better mental health for everyone everywhere. Drawing on the latest evidence available, showcasing examples of good practice from around the world, and voicing people’s lived experience, it highlights why and where change is most needed and how it can best be achieved. It calls on all stakeholders to work together to deepen the value and commitment given to mental health, reshape the environments that influence mental health, and strengthen the systems that care for mental health.
subject: Artykuły
  topic: section
rights: Copyright (c) 2026 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-01-04
publication date: 2026-01-04

Polikarp Girsztowt (1827–1877) and His Few Words about Leprosy
type: item
description: Leprosy, although it did not occur directly on Polish soil, aroused the interest of doctors, especially those associated with Warsaw and the tsarist University of Warsaw. Among them, a special place is occupied by Polikarp Girsztowt, who devoted a lot of space to the problem of this disease in his unfinished book General and specific surgery, referring to the most outstanding experts in the problem.
subject: Artykuły
  topic: section
subject: leprosy
  topic: keywords
subject: Polikarp Girsztowt
  topic: keywords
subject: medical science history
  topic: keywords
creator: Maria J. Turos
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-05-07
publication date: 2025-05-07
starting page: 103
ending page: 108

The Absence of Leprosy in the Polish Population from the 16th to the 21st Century
type: item
description: Leprosy appeared in Poland in the 13th century and eventually disappeared as an endemic disease by the 16th century. Since then, there has never been any local transmission. For over 500 years, only sporadic imported cases have been diagnosed (the last 2 in 2019). Historical data, supported by research on the Polish community in Brazil, indicate a significant resistance of the Polish population to the disease. Further studies should be conducted. However, mass emigration poses a potential threat of reintroducing leprosy to Poland.
subject: Artykuły
  topic: section
subject: Hansen’s disease in Poland
  topic: keywords
subject: autochthonous (native) and imported cases
  topic: keywords
subject: population immunity
  topic: keywords
subject: potential disease reintroduction
  topic: keywords
creator: Józef Piotr Knap
creator: Wacław Leszek Nahorski
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-05-07
publication date: 2025-05-07
starting page: 90
ending page: 102

Leprosy in XXIst Europe
type: item
description: Leprosy (Hansen’s disease) is one of the oldest known infectious diseases and, although now entirely curable, remains a significant global health concern. In Europe, cases of Hansen’s disease are rare and often underrecognized. The disease can be classified into 2 categories: autochthonous (native) cases and imported cases, primarily originating from endemic regions. Autochthonous cases persist in a few European countries, including Spain, Portugal, Greece, Italy, Russian Federation, and Estonia, where small, low endemicity foci remain. These cases are often familial and can persist over long periods due to localized transmission, despite gradual declines in prevalence. The eradication of such cases poses challenges due to the disease’s prolonged incubation period and potential for chronic persistence.
subject: Artykuły
  topic: section
subject: Leprosy (Hansen’s disease)
  topic: keywords
subject: autochthonous (native) cases
  topic: keywords
subject: imported cases
  topic: keywords
creator: Józef Piotr Knap
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-05-07
publication date: 2025-05-07
starting page: 78
ending page: 89

Rickettsial Infections and Q Fever as Underestimated Health Threats to Humans
type: item
description: Rickettsial diseases and Q fever are infectious zoonoses that are rarely considered in the differential diagnosis in everyday medical practice. Improperly collected epidemiological interview and a relatively uncharacteristic clinical picture result in significant diagnostic difficulties and underestimated assessment of its frequency in the human population. The paper describes the nature of the aetiological factors of these unusual infections, discusses the transmission routes of the pathogens, as well as clinical expression and principles of diagnostic and therapeutic procedures. The publication is a review based on the analysis of available scientific literature. Microorganisms of the genus Rickettsia, for which ticks are vectors, cause spotted fevers in humans. R. slovaca and R. raoultii are responsible for SENLAT (scalp eschar and neck lymphadenopathy after tick bite) while R. monacensis causes a disease similar to Mediterranean spotted fever. Typical symptoms of SENLAT include eschar at the site of the tick bite, lymphadenopathy, and local alopecia. R. helvetica infection can have a mild course with fever, headache, and muscle pain. The disease can also manifest with spotted skin rash, persistent muscle weakness, pericarditis or meningitis. Frequent R. monacensis symptoms include fever, headache, rash, and an inoculation eschar. Bacteria belonging to the genus Rickettsia can be classified into the following phylogenetic groups: ancestral, spotted fever group, typhus group, and a relatively recently identified transitional group. According to another systematic classification, these microorganisms can also be assigned to the following categories: spotted fever group, typhus group, Rickettsia bellii group, and R. canadensis group. The spotted fever group Rickettsia species found in Poland include R. slovaca, R. raoultii, R. helvetica, and R. monacensis. Vectors for these bacteria include ticks such as Ixodes ricinus and Dermacentor reticulatus. It is suggested th…
subject: Artykuły
  topic: section
subject: tick-borne diseases
  topic: keywords
subject: Rickettsial infections
  topic: keywords
subject: SENLAT
  topic: keywords
subject: Coxiella burnetii
  topic: keywords
subject: Q fever
  topic: keywords
subject: epidemiology
  topic: keywords
subject: risk factors
  topic: keywords
subject: clinical picture
  topic: keywords
subject: prevention
  topic: keywords
creator: Marta Szczygieł
creator: Dawid Woszczyk
creator: Gabriela Korzańska
creator: Aleksandra Lewczuk
creator: Radosław Gryczewski
creator: Sebastian Chwal
creator: Anna Werner
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-07-01
publication date: 2025-07-01
starting page: 63
ending page: 73
doi: 10.26399/rmp.v31.2.2025/m.szczygiel/d.woszczyk/g.korzanska/a.lewczuk/

The Role of Ticks in the Epidemiology of Selected Transmissible Infectious Diseases
type: item
description: Tick-borne diseases constitute a highly significant and continuously increasing health problem in Poland and Europe. The aim of the study is to discuss the most common infections caused by Borrelia burgdorferi s.l. and tick-borne encephalitis viruses, which are the most frequently reported tick-borne diseases in humans in European countries. The analysis included information on the nature of the etiological agent, clinical symptoms, diagnostic methods, treatment, and epidemiology of the mentioned diseases, collected based on current medical publications available in scientific databases. The study illustrates the scale of the problem and also draws attention to proper prophylaxis and appropriately selected diagnostics for patients with symptoms of infectious diseases.
subject: Artykuły
  topic: section
subject: tick-borne diseases
  topic: keywords
subject: Lyme disease
  topic: keywords
subject: tick-borne encephalitis
  topic: keywords
subject: epidemiology
  topic: keywords
subject: clinical symptoms
  topic: keywords
subject: diagnostics
  topic: keywords
subject: prevention
  topic: keywords
subject: treatment
  topic: keywords
creator: Gabriela Korzańska
creator: Roksana Niciak
creator: Aleksandra Lewczuk
creator: Marta Szczygieł
creator: Radosław Gryczewski
creator: Sebastian Chwal
creator: Dawid Woszczyk
creator: Anna Werner
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-07-01
publication date: 2025-07-01
starting page: 52
ending page: 62
doi: 10.26399/rmp.v31.2.2025/g.korzanska/r.niciak/a.lewczuk/m.szczygiel/r.gryczewski/

Neglected Tick-Borne Diseases with a High Epidemiological Risk of Expansiveness
type: item
description: Tick-borne diseases constitute a group of unique infections with a gradually expanding geographical spread, extremely diverse, often uncharacteristic clinical expression and increasing pathogenicity for humans. Due to the promotion of an active lifestyle associated with tourist and recreational activities in the natural environment, often in forested areas, regions of lush meadows and wild pastures, the risk of accidental transmission of tick-borne pathogens to the human body is significantly increasing. On the other hand, prolonged life expectancy, often accompanying chronic diseases that reduce the efficiency of the immune system, as well as widely used immunosuppressive or immunomodulatory therapies are factors that significantly increase the risk of developing more severe symptoms and long-term clinical consequences of these rarely suspected infections. Anaplasmosis Etiological factor Human granulocytic anaplasmosis (HGA), formerly called granulocytic ehrlichiosis, is an infectious disease caused by microorganisms of the species Anaplasma phagocytophilum (formerly Ehrlichia phagocytophilum). These are Gram-negative bacteria, obligatory intracellular parasites, showing tropism to human neutrophilic granulocytes. Development cycle This disease can develop both in humans and animals. Infections have been recorded in numerous species of domestic and wild animals. Fatal cases have been observed among sheep, cattle, reindeer, deer, moose, dogs, and humans. The most common cause of HGA is a tick bite from the genus Ixodes. In Poland and Europe, this is usually I. ricinus. The presence of A. phagocytophilum has also been confirmed in other tick species occurring in Europe, such as I. hexagonus, I. trianguliceps, and I. persulcatus. Bacterial strains pathogenic to humans can be transmitted by ticks through transmission from horses, dogs, some species of ruminants, hedgehogs, foxes, or wild boars. Infection can also occur transplacentally, through blood transfusion from a…
subject: Artykuły
  topic: section
subject: tick-borne diseases
  topic: keywords
subject: anaplasmosis
  topic: keywords
subject: babesiosis
  topic: keywords
subject: bartonellosis
  topic: keywords
subject: tularemia
  topic: keywords
subject: epidemiology
  topic: keywords
subject: clinical picture
  topic: keywords
subject: diagnostics
  topic: keywords
subject: prevention
  topic: keywords
subject: treatment
  topic: keywords
creator: Aleksandra Lewczuk
creator: Radosław Gryczewski
creator: Sebastian Chwal
creator: Marta Szczygieł
creator: Gabriela Korzańska
creator: Roksana Niciak
creator: Dawid Woszczyk
creator: Anna Werner
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-07-01
publication date: 2025-07-01
starting page: 39
ending page: 51
doi: 10.26399/rmp.v31.2.2025/a.lewczuk/r.gryczewski/s.chwal/m.szczygiel/

Actinomycosis as an Unexpected Cause of Chronic General- ized Lymphadenopathy
type: item
description: Cervicofacial actinomycosis is the most common and classic form of a rare disease caused by bacteria belonging to the Actinomyces genus, but it sporadically causes generalized lymphadenopathy. The slow growth of the microorganism on in vitro media and the specific requirements of microbiological culture often make its isolation from biological material collected from swabs and tissue biopsies difficult. Clinical manifestations of actinomycosis may mimic malignancies of the head or neck, in which a delay in establishing a final clinical diagnosis is particularly unfavorable, such as Hodgkin’s or nonHodgkin’s lymphomas, cancer of the thyroid, oral cavity, pharynx and larynx, lung cancer or metastases from other internal organs. In the study, we present the case of a 43year old patient who was admitted to the university department for a differential diagnosis of cervical and axillary lymphadenopathy with suspected parasitic infection. Previously performed pathomorphological examinations of the material obtained from numerous lymph node biopsies did not confirm any neoplastic disease, and the image of the pathological changes observed in the computed tomography scan indicated a reactive inflammatory process. The enhanced multidirectional diagnostics was performed for infectious and connective tissue diseases, which failed to identify the cause of chronic lymphadenopathy. Retrospective microbiological revision of histopathological samples from enlarged lymph nodes allowed for the unexpected confirmation of actinomycosis. The patient received combined, targeted systemic antibiotic therapy, which resulted in regression of inflammatory changes in the lymph nodes. The presented case demonstrates the need to consider rare infectious diseases in the differential diagnosis of lymphadenopathy in everyday medical practice and draws attention to the possibility of revision of the diagnosis using preserved pathomorphological preparations.
subject: Artykuły
  topic: section
subject: Actinomycosis
  topic: keywords
subject: Actinomyces spp.
  topic: keywords
subject: generalized lymphadenopathy
  topic: keywords
subject: differential diagnosis
  topic: keywords
subject: histopathology
  topic: keywords
subject: lymphoma
  topic: keywords
creator: Marta Szczygieł
creator: Radosław Siemionek
creator: Marek Spichalski
creator: Mateusz Hałas
creator: Małgorzata Paul
rights: Copyright (c) 2026 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-07-01
publication date: 2025-07-01
starting page: 32
ending page: 38

Effect of Caesarean Section on Subsequent Child Development
type: item
description: Caesarean section is a method of terminating pregnancy and the most commonly performed obstetric surgical procedure worldwide, with the number of cesarean sections in Poland and globally continuously increasing. Obstetric and non-obstetric indications for cesarean section have been strictly defined by the Polish Gynecological Society. Currently, the most commonly used technique for this operation is the transverse incision via the Pfannenstiel approach. Surgical termination of pregnancy may have numerous consequences for child development. Children born by cesarean section often do not meet all the conditions necessary to initiate proper respiratory function and appropriate cardiovascular adaptation. Different colonization of the intestines by microorganisms in infants born by cesarean section is responsible for disturbances in the bacterial flora of the gastrointestinal tract, which may increase the risk of obesity and have many other serious consequences, such as the development of various diseases. Results of individual studies indicate that cesarean section carries an increased risk of asthma, allergic diseases, systemic connective tissue disorders, immune deficiencies, and intestinal diseases in the later development of the child. Children born by cesarean section, compared to those born naturally, are exposed during delivery to different physical, microbiological, hormonal, and medical factors. These influence physiological processes and consequently shape the child's health not only in the neonatal period but also during adolescence and adulthood.
subject: Artykuły
  topic: section
subject: caesarean section
  topic: keywords
subject: child development
  topic: keywords
subject: respiratory system
  topic: keywords
subject: cardiovascular system
  topic: keywords
subject: asthma
  topic: keywords
subject: microbiota
  topic: keywords
subject: allergies
  topic: keywords
creator: Julia Nosko
creator: Adrianna Truszyńska-Zawisza
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-09-11
publication date: 2025-09-11
doi: 10.26399/rmp.v31.3.2025/j.nosko/a.truszynska-zawisza

Shingles and Its Preventative Possibilities in Poland
type: item
description: Shingles is an infectious disease caused by the varicella-zoster virus (Varicella-Zoster Virus, VZV). The virus reactivates in people who have had chickenpox in the past and after close contact with children with chickenpox, usually within family. It is estimated that almost every person has had contact with VZV in their lifetime, which translates into a potentially high incidence of shingles. Having shingles is associated with the risk of serious complications, both local and neurological, which can significantly reduce the quality of life of patients. Treatment of shingles and its complications is difficult and poses a great challenge, which also emphasizes the importance of preventive measures. This article discusses shingles as a disease and the possibilities of its prevention in Poland.
subject: Artykuły
  topic: section
subject: shingles
  topic: keywords
subject: VZV
  topic: keywords
subject: HZ
  topic: keywords
subject: postherpetic neuralgia
  topic: keywords
subject: shingles vaccination
  topic: keywords
creator: Jakub Błotny
creator: Justyna Tymińska
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-09-11
publication date: 2025-09-11
doi: 10.26399/rmp.v31.3.2025/j.blotny/j.tyminska

Paradoxical Skin Reaction in Patients with Rheumatoid Arthritis Treated with TNF-α Inhibitors
type: item
description: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive joint damage driven by ongoing inflammation. The introduction of innovative therapies, including biological drugs, has significantly improved patients' quality of life by reducing the severity of joint destruction and slowing disease progression. Some patients undergoing biological therapy may experience adverse effects, including local skin reactions at the injection site and, much more rarely, generalized changes such as de novo psoriasis and other paradoxical skin reactions. This paper describes 2 cases of female patients with a long history of RA (68 and 73 years old), in whom administration of TNF-α inhibitors (Certolizumab pegol in the first, Etanercept in the second) led to allergic urticaria and paradoxical psoriasis. After discontinuation of these drugs, gradual symptom resolution was observed, allowing for alternative treatment with Tocilizumab – a drug from the IL-6 inhibitor group. Reduction of disease symptoms and regression of skin symptoms were achieved. According to literature data, using a drug with the same mechanism of action in the next line of therapy would be associated with a higher risk of psoriasis recurrence. The presented cases emphasize the need for careful monitoring of adverse effects of drugs used in biological therapy, especially regarding the induction of skin complications, not only local but also generalized.
subject: Artykuły
  topic: section
subject: rheumatoid arthritis
  topic: keywords
subject: paradoxical skin reactions
  topic: keywords
subject: psoriasis
  topic: keywords
subject: biological therapy
  topic: keywords
subject: TNF-α inhibitors
  topic: keywords
creator: Aleksandra Mokrzycka
creator: Piotr Dąbrowski
creator: Bogdan Kolarz
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-09-11
publication date: 2025-09-11
doi: 10.26399/rmp.v31.3.2025/a.mokrzycka/p.dabrowski/b.kolarz

Dapsone – Should It Be Considered as a Treatment Option for Acne, Rosacea and Hidradenitis Suppurativa?
type: item
description: Dapsone is a chemical compound belonging to the sulfone group, primarily used as a first-line treatment for leprosy. Beyond this indication, it possesses a broad spectrum of antibacterial, antiparasitic, immunosuppressive/immunomodulatory, and anti-inflammatory properties, playing a key role in the management of numerous dermatological conditions. It is considered the first-line therapy for dermatitis herpetiformis and erythema elevatum diutinum. Additionally, it is employed in the treatment of other skin disorders such as bullous pemphigoid, mucous membrane pemphigoid, cutaneous lupus erythematosus, among others. This article discusses the therapeutic potential of dapsone in the treatment of acne vulgaris, rosacea, and hidradenitis suppurativa. Furthermore, an overview of dosing regimens used in other dermatological diseases is provided.
subject: Artykuły
  topic: section
subject: acne vulgaris
  topic: keywords
subject: dapsone
  topic: keywords
subject: hidradenitis suppurativa
  topic: keywords
subject: rosacea
  topic: keywords
creator: Paulina Petrosyan-Chrościcka
creator: Bartłomiej Kwiek
rights: Copyright (c) 2025 Review of Medical Practice https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2025-09-11
publication date: 2025-09-11
doi: 10.26399/rmp.v31.3.2025/p.petrosyan-chroscicka/b.kwiek