Resumen
Dapsone is a chemical compound belonging to the sulfone group, primarily used as a first-line treatment for leprosy. Beyond this indication, it possesses a broad spectrum of antibacterial, antiparasitic, immunosuppressive/immunomodulatory, and anti-inflammatory properties, playing a key role in the management of numerous dermatological conditions. It is considered the first-line therapy for dermatitis herpetiformis and erythema elevatum diutinum. Additionally, it is employed in the treatment of other skin disorders such as bullous pemphigoid, mucous membrane pemphigoid, cutaneous lupus erythematosus, among others. This article discusses the therapeutic potential of dapsone in the treatment of acne vulgaris, rosacea, and hidradenitis suppurativa. Furthermore, an overview of dosing regimens used in other dermatological diseases is provided.
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