Vol. 30 No. 4 (2024): REVIEW OF MEDICAL PRACTICE
Dear Readers,
I am handing over to you the fourth issue of the quarterly “Review of Medical Practice” this year. In this issue we present you with several interesting publications, among them a study entitled Melioidoza – szczególnie niebezpieczna choroba nie tylko tropików. Powstawanie globalnego zagrożenia (Melioidosis – a Deadly Disease Emerging Threat Beyond Tropics. Emerging of Global Risk) by the Mazovian provincial consultant in marine and tropical medicine. He points out that one of the undesirable consequences of globalisation is the transmission of human, animal and plant diseases from their areas of occurrence to other continents where they did not previously occur. The article discusses the worrying features of melioidosis as a disease of global concern due to its tendency to spread globally, its clinical features and the great plasticity of the germ capable of surviving in extremely adverse environmental conditions.
In the article Postępowanie diagnostyczne w przypadku podejrzenia melioidozy skórnej po powrocie z Azji Południowo-Wschodniej. Istotna wartość szybkich badań molekularnych (RT-PCR) (Diagnostic Procedures in the Case of Strong Suspicion of Dermal Melioidosis Imported from South-Eastern Asia. Essential Value of Rapid Molecular Procedures (RT-PCR)), the case of a 28-year-old female patient who developed purulent and purulent skin lesions with epidemiological, clinical and microbiological similarities to melioidosis after her return from Southeast Asia is presented. The pattern and rationale for the diagnostic management of suspected cases of this particularly dangerous disease are discussed.
I also recommend the article The Occurrence of the Very Rare Autosomal Dominant Spinocerebellar Ataxia Subtypes SCA15, SCA31, and SCA36 in Poland and Its Implications for Clinical Practice. Autosomal dominant spinal-cerebellar ataxias (SCAs) are a genetically and clinically heterogeneous group of conditions characterised by degenerative changes in the brain and spinal cord and a varied disease onset. This article presents the results of a study of 350 patients diagnosed with genetically determined ataxia. In none of the patients was a large deletion detected in the ITPRI gene causing
SCA15. In contrast, an expansion of intron hexonucleotide repeats in the NOP56 gene causing SCA36 was found in 11 patients. This indicates the need for genetic testing for SCA36 in the diagnostic management of patients with a suspected rare form of hereditary ataxia.
Sincerely,
Editor-in-Chief
Anna Wilmowska-Pietruszyńska, MD, Prof. UŁa
